Author(s): Junaid Ahmad,1 Shamila Ashraf,2 Kamran Khalid3
Received: 13/07/2023 | Published: 31/10/2023 | Pages: 57-61 |
Background: Antimicrobial susceptibility patterns play an important part in the management of burn wound infections, a common cause of morbidity & mortality. We evaluated the antibiogram of burn wounds at Jinnah Burn and Reconstructive Surgery Center, Lahore, Pakistan which is one of largest burn centers in the country.
Methodology: Retrospective observational study of burn patients. Our study included all kinds of burns and all admitted patients with all ages, total burn surface area 01-80%. Wound cultures and sensitivity done on wounds swabs by culture and disc diffusion methods.
Results: There were 1774 cases included in this study. The most common organism isolated in this study was Pseudomonas species, followed by Acinetobacter species, Klebsiela. Colistin showed best sensitivity against gram negative bacteria isolated in this study. Other antibiotics discs used were Imipenem, Meropenem, Doxycycline, Ciprofloxacine, Levofloxacine, and others
Conclusion: Pseudomonas species is the most common organism found in cultures of burn wounds and Colistin shows best sensitivity results against all bacteria found in our reports including Klebsiella and, Acinetobacter species.
Keywords: Antibiogram, Acinetobacter, burn wounds, burn center, wound culture.
- Hubab M, Maab H, Hayat A, Ur Rehman M. Burn Wound Microbiology and the Antibiotic Susceptibility Patterns of Bacterial Isolates in Three Burn Units ofAbbottabad, J Burn Care Res. 2020 Nov 30;41(6):12071211
- Infection control in severely burned patients. World J Crit Care Med. 2012 Aug 4;1(4):94-101.
- Deirdre Church, Sameer Elsayed, Owen Reid, Brent Winston, and Robert Lindsay. Burn Wound Infections. Clin Microbiol Rev. 2006 Apr; 19(2): 403-434.
- Markiewicz-Gospodarek A, Koziol M, Tobiasz M, Baj J, Radzikowska-Btichner E, Przekora A. Burn Wound Healing: Clinical Complications, Medical Care, Treatment, and Dressing Types: The Current State of Knowledge for Clinical Practice. Int J Environ Res Public 2022 Jan 25;19(3):1338.
- N Agnihotri, V Gupta, R.M Joshi. Aerobic bacterial isolates from burn wound infections and their antibiograms—a five-year study. Burn 2004; 30(3): 241-243
- Song J, Kim J, Lee J, et al. Microbiologic and clinical characteristics of burn wound infections in a Korean tertiary care center. Annals of Burn and Fire 2016;29(4):184-189.
- Tan, S.Y., Khan, R.A., Khalid, K.E. et al. Correlation between antibiotic consumption and the occurrence of multidrug-resistant organisms in a Malaysian tertiary hospital: a 3-year observational study. Sci Rep 12, 3106 (2022)
- Sakkas H, Bozidis P, IliaA, Mpekoulis G, Papadopoulou Antimicrobial Resistance in Bacterial Pathogens and Detection of Carbapenemases in Klebsiella pneumoniae Isolates from Hospital Wastewater. Antibiotics. 2019; 8(3):85.
- El Hamzaoui, A. Barguigua, S. Larouz, M. Maouloua. Epidemiology of burn wound bacterial infections at a Meknes hospital, Morocco, New Microbes and New Infections. 2020:38 (100764)
- Ahmad J,khalid FA, Shahzad I ,Tabassum G,Khan QA, Ashraf S ,Tarar MN. A Retrospective Study ofAntibiogram in One of the Largest Burn Center in Pakistan. JAIMC2022;20(1): 13-16
- JunaidAhmad, FarrukhAslam Khalid, Mehreen Fatima, Moazzam Nazeer Tarar. Extensively Resistant Pathogens and TheirAntimicrobial Profile in Patients Expired in ICU of a Burn Center in Lahore Pakistan. Pakistan Journal of Plastic Surgeons 2017: 5 (3); 1-5
- Leekha S, Terrell CL, Edson RS. General principles of antimicrobial therapy. Mayo Clin Proc. 2011 Feb; 86(2): 156-67
- Dai T, Huang YY, Sharma SK, Hashmi JT, Kurup DB, Hamblin MR. Topical antimicrobials for burn wound Recent Pat Antiinfect Drug Discov. 2010 Jun; 5(2):124-51.
- Cartotto R. Topical antimicrobial agents for pediatric Burns & trauma. 2017 Dec 1;5.
- Kaye ET. Topical antibacterial agents. Infectious disease clinics ofNorth America. 2000 Jun 1 ; 14(2): 321 -39.
- Mea HJ, Yong PVC, Wong EH. An overview ofAcinetobacter baumannii pathogenesis: Motility, adherence and biofilm formation. Microbiol Res. 2021 Jun;247:126722. doi: 10.1016/j.micres.2021.126722. Epub 2021 Feb PMID: 33618061.
- Malcolm D. Eve, John A.D. Settle, J. Howard Smith. Amikacin in a burn unit: 2 years’ experience. Burns,Volume 7, Issue 6,1981,Pages 418-424
All published material becomes the sole property of the Pakistan Journal of Plastic Surgery, copyrighted by the Pakistan Association of Plastic Surgeons (PAPS). By submitting an article or brief communication, all authors agree to these conditions.
During the submission process, all authors have required to complete a copyright transfer agreement, “Author Consent form” By completing the copyright transfer agreement, you are transferring copyright of figures, tables, videos, and the content of the manuscript to the Pakistan Association of Plastic Surgeons (PAPS).
If you do not wish to or cannot transfer copyright of some or all of your content, please contact the editorial office at pjpspakistan@gmail.com.